Description

1H-Azirine CAS NO 157-17-5 is a highly reactive, three-membered heterocyclic compound containing a nitrogen atom, which serves as a fundamental building block in advanced organic synthesis. Its strained ring structure makes it a valuable and versatile precursor for constructing complex nitrogen-containing molecules, including pharmaceuticals and agrochemicals. This compound is essential for research chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries seeking to introduce novel aziridine or other functionalized amine frameworks.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those containing aziridine or complex amine moieties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with unique modes of action.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel nitrogen-donor ligands and organocatalysts.
• Academic and Industrial Research: A critical reagent for methodological studies in organic chemistry, including cycloaddition and ring-opening reactions.
• Material Science: Investigated for the development of advanced functional materials, such as conductive polymers or photoactive compounds.

Basic Information

Product Name	1H-Azirine
CAS No.	157-17-5
Molecular Formula	C2H3N
Molecular Weight	41.05 g/mol
Synonyms	Azirine; 1H-Azirine; Azacyclopropene; Vinylenimine; 1-Azirine; Ethylenimine, 1H-; 2H-Azirine (tautomer); UNII-9Q2I6S6B1F
EINECS	205-857-5

Quality Control

Our 1H-Azirine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profile. We are committed to meeting the stringent requirements of research and development applications, with specifications available to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and easily oxidized nature, this product should be stored under an inert atmosphere (e.g., nitrogen or argon) at recommended temperatures (typically 2-8°C or as specified). Keep the container in a cool, dry, well-ventilated place away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Report and comply with limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.