Description

Physalien (CAS NO 144-67-2) is a naturally occurring carotenoid pigment, specifically a dipalmitate ester of zeaxanthin, known for its vibrant red-orange color. This compound is valued for its potent antioxidant properties and its role as a key colorant in various formulations. It serves as a critical ingredient for manufacturers in the nutraceutical, cosmetic, and food industries seeking natural, functional additives.

Application

• Nutraceutical & Dietary Supplements: Utilized as an active ingredient in antioxidant formulations and vision health supplements due to its role as a precursor to macular pigments.
• Natural Food Colorant: Imparts a stable red-orange hue to beverages, confectionery, dairy products, and baked goods, appealing to the clean-label trend.
• Cosmetics & Personal Care: Incorporated into skincare products (creams, serums) for its antioxidant benefits and as a natural pigment in color cosmetics.
• Animal Feed & Aquaculture: Used to enhance the coloration of poultry egg yolks, fish flesh (e.g., salmon, trout), and ornamental species.
• Pharmaceutical Research: Serves as a reference standard and an intermediate in the research and development of therapeutic agents targeting oxidative stress.
• Industrial Dyes: Potential application as a natural dye for non-food products where a bio-based colorant is desired.

Basic Information

Product Name	Physalien
CAS No.	144-67-2
Molecular Formula	C72H116O4
Molecular Weight	1045.71 g/mol
Synonyms	Zeaxanthin dipalmitate; Physalin; (3R,3'R)-Zeaxanthin dipalmitate; CI Natural Yellow 27; Natural Orange 6; CAS 144-67-2; All-trans-zeaxanthin dipalmitate
EINECS	205-636-4

Quality Control

Our Physalien is produced and tested under strict quality management systems to ensure batch-to-batch consistency and purity. We provide comprehensive support for food-grade, cosmetic, and nutraceutical applications, with specifications tailored to meet relevant industry standards. A detailed Certificate of Analysis (COA), including assay and impurity profiles, is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) at 2-8°C or as specified on the label. This product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Red-orange to dark red crystalline powder
Identification (HPLC/UV)	Conforms to reference standard
Assay (HPLC)	≥ 90.0% (as Zeaxanthin dipalmitate)
Solubility	Soluble in chloroform, DMSO; practically insoluble in water
Loss on Drying	≤ 2.0 %
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents	Meets ICH guidelines
Microbiological Analysis	Meets target application standards

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.