Description

1-Chloro-2,4-dimethoxy-5-nitrobenzene is a versatile nitroaromatic compound characterized by its distinct chloro, dimethoxy, and nitro substituents. This specific substitution pattern makes it a valuable chemical intermediate and building block in advanced organic synthesis. It is primarily sought after by manufacturers and R&D departments in the pharmaceutical, agrochemical, and dye and pigment industries for the development of complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a substituted nitrobenzene scaffold.
• Agrochemical Synthesis: Used as a building block for developing herbicides, pesticides, and fungicides, leveraging its reactive nitro and chloro groups.
• Dye and Pigment Manufacturing: Serves as an intermediate in the production of complex azo dyes and other colorants due to its aromatic nitro structure.
• Organic Synthesis & Research: A valuable reagent for academic and industrial research in heterocyclic chemistry and material science.
• Chemical Intermediate: Used in further functionalization reactions, such as nucleophilic aromatic substitution or reduction of the nitro group to an amine.

Basic Information

Product Name	1-Chloro-2,4-Dimethoxy-5-Nitrobenzene
CAS No.	119-21-1
Molecular Formula	C8H8ClNO4
Molecular Weight	217.61 g/mol
Synonyms	2,4-Dimethoxy-1-chloro-5-nitrobenzene; 5-Nitro-2,4-dimethoxychlorobenzene; 1-Chloro-2,4-dimethoxy-5-nitrobenzene; 2,4-Dimethoxy-5-nitrochlorobenzene; NSC 403697; 5-Chloro-2,4-dinitroanisole (isomer reference); Benzene, 1-chloro-2,4-dimethoxy-5-nitro-
EINECS	204-310-1

Quality Control

Our 1-Chloro-2,4-Dimethoxy-5-Nitrobenzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.