Description

tert-Butyl Chloroacetate CAS NO 107-59-5 is a versatile organic ester and a key alkylating agent in advanced chemical synthesis. Its primary value lies in its reactive chloroacetyl group protected by the bulky tert-butyl moiety, making it an essential building block for constructing complex molecules with high selectivity. This compound is critically needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the chloroacetate functional group.
• Agrochemical Synthesis: Used in the production of herbicides, pesticides, and plant growth regulators where its alkylating properties are utilized.
• Peptide Chemistry: Serves as a reagent for the protection and modification of amino acids during peptide synthesis.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers and resins.
• Organic Synthesis Reagent: Employed in various organic transformations, including esterifications and nucleophilic substitution reactions, to introduce tert-butoxycarbonyl or chloroacetyl groups.
• Chemical Research & Development: A valuable tool for medicinal chemists and researchers developing new molecular entities and exploring structure-activity relationships.

Basic Information

Product Name	tert-Butyl Chloroacetate
CAS No.	107-59-5
Molecular Formula	C6H11ClO2
Molecular Weight	150.60 g/mol
Synonyms	Chloroacetic Acid tert-Butyl Ester; 2-Chloroacetic Acid 1,1-Dimethylethyl Ester; tert-Butyl 2-Chloroacetate; t-Butyl Chloroacetate; 1,1-Dimethylethyl Chloroacetate; (CH3)3COCOCH2Cl
EINECS	203-506-5

Quality Control

Our tert-Butyl Chloroacetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, strong oxidizing agents, and sources of ignition. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.420 - 1.425
Density (20°C)	1.05 - 1.10 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.