Description

4-Methylthiazole-5-Carboxaldehyde is a versatile heterocyclic aldehyde building block with significant synthetic utility. This compound matters as a key intermediate in the production of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries that need it include pharmaceutical R&D for creating active pharmaceutical ingredients (APIs), agrochemical manufacturers for developing novel crop protection agents, and fine chemical producers for synthesizing flavors, fragrances, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those containing thiazole motifs.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and fungicides, leveraging its reactive aldehyde group for structural diversification.
• Flavor & Fragrance Industry: Serves as a building block for creating complex aroma chemicals and flavoring agents due to its heterocyclic structure.
• Material Science Research: Employed in the synthesis of organic ligands, coordination polymers, and advanced organic electronic materials.
• Chemical Research & Development: A valuable reagent for organic synthesis, including condensation reactions, heterocycle formation, and as a scaffold for library generation in medicinal chemistry.
• Dye & Pigment Intermediate: Can be utilized in the synthesis of specialized dyes and pigments where the thiazole ring contributes to color and stability properties.

Basic Information

Product Name	4-Methylthiazole-5-Carboxaldehyde
CAS No.	82294-70-0
Molecular Formula	C5H5NOS
Molecular Weight	127.16 g/mol
Synonyms	5-Formyl-4-methylthiazole; 4-Methyl-5-thiazolecarboxaldehyde; 4-Methylthiazole-5-carbaldehyde; 4-Methyl-1,3-thiazole-5-carbaldehyde; 5-Aldehyde-4-methylthiazole; 4-Methyl-5-formylthiazole; 4-Methyl-5-thiazolecarbaldehyde; 4-Methyl-1,3-thiazole-5-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-Methylthiazole-5-Carboxaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its properties of being light-sensitive and easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.