Nitrofurans

Synthetic Anti-Infective Drugs

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Nitrofurans

Nitrofurans are synthetic antimicrobial agents characterized by a nitrofuran ring that undergoes intracellular reduction to generate reactive intermediates capable of damaging bacterial DNA, ribosomal proteins, and metabolic enzymes. These drugs, including nitrofurantoin, furazolidone, and nitrofurazone, exhibit broad-spectrum activity against Gram-positive and Gram-negative bacteria, particularly in urinary and gastrointestinal infections. Nitrofurantoin remains a first-line therapy for uncomplicated urinary tract infections due to its high urinary concentrations and limited systemic distribution. Nitrofurans act through multiple mechanisms, reducing the risk of resistance, although long-term use may be limited by pulmonary, hepatic, or neurological toxicity. Despite safety considerations, nitrofurans remain valuable in both human and veterinary medicine due to their efficacy and low cross-resistance potential.

1-Benzylidene-5-[(5-Nitrofuran-2-Yl)Methylene]Carbonohydrazide CAS NO 4932-11-0

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CAS No.:4932-11-0

Grade:Pharmacy Grade

Content:99.90%

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n-Methyl-3-(5-Nitrofuran-2-Yl)-n-Nitroso-1H-1,2,4-Triazol-5-Amine CAS NO 41735-28-8

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CAS No.:41735-28-8

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n-Ethyl-n-Nitro-3-(5-Nitrofuran-2-Yl)-1H-1,2,4-Triazol-5-Amine CAS NO 41735-30-2

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CAS No.:41735-30-2

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Content:99.90%

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1,n-Dimethyl-3-(5-Nitrofuran-2-Yl)-1H-1,2,4-Triazol-5-Amine CAS NO 41735-41-5

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CAS No.:41735-41-5

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1-Methyl-5-(5-Nitrofuran-2-Yl)-1H-1,2,4-Triazol-3-Amine CAS NO 41735-42-6

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CAS No.:41735-42-6

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Content:99.90%

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n-[1-Methyl-5-(5-Nitro-2-Furanyl)-1H-1,2,4-Triazol-3-Yl]Acetamide CAS NO 41735-43-7

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CAS No.:41735-43-7

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4-Methyl-n-Nitro-5-(5-Nitrofuran-2-Yl)-4H-1,2,4-Triazol-3-Amine CAS NO 41735-51-7

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CAS No.:41735-51-7

Grade:Pharmacy Grade

Content:99.90%

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4-Ethyl-5-(5-Nitrofuran-2-Yl)-4H-1,2,4-Triazol-3-Amine CAS NO 41735-52-8

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CAS No.:41735-52-8

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Content:99.90%

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