Description

Dimethylammoniumdichlorotri(μ-chloro)bis[(S)-(-)-2,2'-bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl]diruthenate(II)[NH2Me2][{RuCl((S)-H8-binap)}2(μ-Cl)3] is a high-value, chiral ruthenium complex salt designed for advanced asymmetric catalysis. This compound matters because it serves as a highly efficient and selective pre-catalyst for enantioselective hydrogenation and other critical transformations in fine chemical synthesis. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control to produce high-purity enantiomers.

Application

• Asymmetric Hydrogenation Catalyst: A key pre-catalyst for the enantioselective reduction of prochiral ketones, olefins, and imines to produce chiral alcohols, amines, and other intermediates.
• Pharmaceutical Intermediate Synthesis: Enables the production of single-enantiomer active pharmaceutical ingredients (APIs) for drugs targeting central nervous system, cardiovascular, and metabolic diseases.
• Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators where biological activity is stereospecific.
• Fine Chemical and Fragrance Production: Facilitates the creation of enantiomerically pure flavors, fragrances, and advanced material precursors.
• Academic and Industrial R&D: A critical tool for method development and discovery chemistry in asymmetric synthesis and organometallic catalysis.
• Process Chemistry Optimization: Employed for scaling up enantioselective transformations from laboratory to pilot plant and commercial production.

Basic Information

Product Name	Dimethylammoniumdichlorotri(μ-chloro)bis[(S)-(-)-2,2'-bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl]diruthenate(II)[NH2Me2][{RuCl((S)-H8-binap)}2(μ-Cl)3]
CAS No.	944451-12-1
Molecular Formula	C92H86Cl5N1P4Ru2
Molecular Weight	1685.79 g/mol
Synonyms	[NH2Me2][{RuCl((S)-H8-BINAP)}2(μ-Cl)3]; Dimethylammonium Trichloro-bis[(S)-(-)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthalene-2,2'-diyl)bis[diphenylphosphine]]-tri-μ-chloro-diruthenate(II); (S)-H8-BINAP Ruthenium Dichloride Dimer Dimethylammonium Salt; [RuCl((S)-H8-binap)]2(μ-Cl)3 NH2Me2; Asymmetric Hydrogenation Catalyst Precursor with H8-BINAP Ligand; Chiral Ruthenium Diphosphine Complex
EINECS	Contact for details

Quality Control

Every batch of this high-purity chiral catalyst is manufactured and analyzed under strict quality control protocols to ensure consistency and performance. Our products undergo rigorous quality testing, including chiral purity verification, to ensure compliance with research and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Ruthenium (Ru) Content	Contact for details
Solubility	Soluble in dichloromethane, toluene; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.