Description

Dichloro{(S)-(-)-5,5'-bis[di(3,5-xylyl)phosphino]-4,4'-bi-1,3-benzodioxole} [(1S,2S)-(-)-1,2-diphenylethylenediamine]ruthenium(II) RuCl2[(S)-dm-segphos][(S,S)-dpen] is a highly sophisticated chiral ruthenium complex designed for asymmetric hydrogenation catalysis. This compound is valued for its exceptional enantioselectivity and catalytic activity in the synthesis of optically pure intermediates. It is an essential catalyst for R&D and production chemists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Asymmetric Hydrogenation Catalyst for the synthesis of chiral pharmaceutical intermediates, including β-amino acids and functionalized ketones.
• Key reagent in the production of Active Pharmaceutical Ingredients (APIs) requiring high enantiomeric purity.
• Catalyst for the enantioselective reduction of functionalized olefins, ketones, and imines in fine chemical synthesis.
• Research and development of novel chiral ligands and metal complexes for catalytic applications.
• Process development and scale-up for green chemistry and sustainable manufacturing routes.
• Manufacture of chiral building blocks for agrochemicals and specialty materials.

Basic Information

Product Name	Dichloro{(S)-(-)-5,5'-bis[di(3,5-xylyl)phosphino]-4,4'-bi-1,3-benzodioxole} [(1S,2S)-(-)-1,2-diphenylethylenediamine]ruthenium(II)
CAS No.	944450-46-8
Molecular Formula	C72H68Cl2N2O4P2Ru
Molecular Weight	1249.12 g/mol
Synonyms	RuCl2[(S)-dm-segphos][(S,S)-dpen]; Dichloro[(S)-(-)-5,5'-bis[di(3,5-xylyl)phosphino]-4,4'-bi-1,3-benzodioxole][(1S,2S)-(-)-1,2-diphenylethylenediamine]ruthenium(II); (S)-DM-SEGPHOS Ru(II) (S,S)-DPEN complex; Ruthenium(II) dichloro[(S)-dm-segphos][(S,S)-dpen]; Asymmetric hydrogenation catalyst Ru-SEGPHOS-DPEN; [RuCl((S)-dm-segphos)((S,S)-dpen)]Cl
EINECS	Contact for details

Quality Control

Our high-value chiral catalysts are produced under strict quality-controlled conditions to ensure batch-to-batch consistency and optimal catalytic performance. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and elemental analysis to confirm identity, purity, and enantiomeric integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. This material is light-sensitive and easily oxidized.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Elemental Analysis	Within theoretical ± 0.4%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.