Description

4-hydroxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine 4-oxide compound with (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol(1:1) is a sophisticated, high-purity organic compound with the CAS number 916329-20-9. This complex molecule is valued for its precise stereochemistry and functional groups, making it a critical advanced intermediate in pharmaceutical research and development. It is primarily utilized by contract research organizations (CROs) and pharmaceutical companies engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the multi-step synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) research.
• Asymmetric Catalysis Research: Used in academic and industrial laboratories to study and develop new asymmetric synthetic methodologies due to its complex structure.
• Ligand Precursor: The molecular framework can be modified for use in developing novel ligands for metal-catalyzed reactions.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical chemistry.
• Process Chemistry Development: Used for scaling up and optimizing synthetic routes during the late-stage development of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	4-hydroxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine 4-oxide compound with (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol(1:1)
CAS No.	916329-20-9
Molecular Formula	C44H36BrN2O5P
Molecular Weight	783.65 g/mol
Synonyms	(1R,2S)-1-(6-Bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol compound with 4-hydroxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine 4-oxide (1:1); 4-Hydroxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine 4-oxide - (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol (1:1); CAS 916329-20-9; 916329-20-9.
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, chiral HPLC, NMR, and mass spectrometry to verify identity, chiral purity, and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a desiccator or under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.