Description

3-Carbamoyl-N,n-Diethyl-1,3,4,6,7,11B-Hexahydro-9,11-Dimethoxy-2H-Benzo[A]Quinolizin-2-Yl Acetate Hydrochloride is a high-purity, complex heterocyclic compound with significant pharmaceutical research value. This compound is critical for its role as a key intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the synthesis of specialized alkaloid-based drugs. The material is supplied with a guaranteed Certificate of Analysis to ensure batch-to-batch consistency for your critical applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of complex alkaloid-derived active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a reference standard or starting material in drug discovery programs targeting neurological or cardiovascular pathways.
• Biochemical Research: Employed in studies investigating the interaction of complex heterocycles with biological receptors and enzymes.
• Process Development & Scale-Up: Utilized by process chemists to develop and optimize robust, scalable synthetic routes for pilot and commercial manufacturing.
• Analytical Standard: Functions as a high-purity standard for method development and validation in quality control laboratories using HPLC, LC-MS, or NMR.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	3-Carbamoyl-N,n-Diethyl-1,3,4,6,7,11B-Hexahydro-9,11-Dimethoxy-2H-Benzo[A]Quinolizin-2-Yl Acetate Hydrochloride
CAS No.	113-69-9
Molecular Formula	C22H33N3O5 • HCl
Molecular Weight	463.98 g/mol
Synonyms	1,3,4,6,7,11b-Hexahydro-9,11-dimethoxy-3-(aminocarbonyl)-2-[(2,2-diethyl-1-oxo-2-ethoxy)ethyl]-2H-benzo[a]quinolizine hydrochloride; Benzo[a]quinolizin-2-yl acetate derivative; 3-Carbamoyl-2-(2,2-diethoxyacetoxy)-9,11-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzo[a]quinolizine hydrochloride; Diethylamino analog of emetine derivative; Emetine-related intermediate; CAS 113-69-9; 2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-3-(aminocarbonyl)-, acetate (ester), hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Carbamoyl-N,n-Diethyl-1,3,4,6,7,11B-Hexahydro-9,11-Dimethoxy-2H-Benzo[A]Quinolizin-2-Yl Acetate Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) documenting all specifications is provided with each shipment to ensure traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a cool, dry place. For long-term stability, store at a controlled room temperature of 15-25°C (59-77°F) in a desiccated environment. Keep the container tightly sealed after each use to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.