Description

(1aR,2S,5aR,8S,9aR,11aR)-8-(Acetyloxy)-1a,2,3,4,5a,6,7,8,9,9a,10,11-dodecahydro-11-methoxy-5a,9,9-trimethyl-13-methylene-5H-2,11a-ethanobenzo[5,6]cyclodec[1,2-b]oxirene-5,12-dione is a high-purity, complex diterpenoid derivative with significant potential as a key synthetic intermediate and research chemical. Its intricate polycyclic structure, featuring an oxirane ring and multiple stereocenters, makes it a valuable scaffold for advanced organic synthesis and pharmaceutical research. This compound is primarily sought by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly for complex natural product analogs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Acts as a precursor for creating new plant protection agents with potential insecticidal or herbicidal activity.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring sophisticated stereochemical control.
• Academic & Institutional Research: Utilized in universities and research institutes for studies in organic synthesis methodology, total synthesis, and chemical biology.
• Biochemical Probe Development: Potential use in developing molecular probes to study biological pathways and enzyme interactions.

Basic Information

Product Name	(1aR,2S,5aR,8S,9aR,11aR)-8-(Acetyloxy)-1a,2,3,4,5a,6,7,8,9,9a,10,11-dodecahydro-11-methoxy-5a,9,9-trimethyl-13-methylene-5H-2,11a-ethanobenzo[5,6]cyclodec[1,2-b]oxirene-5,12-dione
CAS No.	83159-28-8
Molecular Formula	C25H32O7
Molecular Weight	444.52 g/mol
Synonyms	8-Acetoxy-11-methoxy-5a,9,9-trimethyl-13-methylenedodecahydro-2,11a-ethanobenzo[5,6]cyclodeca[1,2-b]oxirene-5,12-dione; Taxinine M; 2,11a-Ethanobenzo[5,6]cyclodeca[1,2-b]oxirene-5,12-dione, 8-(acetyloxy)-1a,2,3,4,5a,6,7,8,9,9a,10,11-dodecahydro-11-methoxy-5a,9,9-trimethyl-13-methylene-, (1aR,2S,5aR,8S,9aR,11aR)-; Taxinine M (8-acetoxy derivative); A derivative of Taxinine
EINECS	Contact for details

Quality Control

Our (1aR,2S,5aR,8S,9aR,11aR)-8-(Acetyloxy)-1a,2,3,4,5a,6,7,8,9,9a,10,11-dodecahydro-11-methoxy-5a,9,9-trimethyl-13-methylene-5H-2,11a-ethanobenzo[5,6]cyclodec[1,2-b]oxirene-5,12-dione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere at lower temperatures (e.g., -20°C) to maximize stability. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.