Description

O-(N-Acetyl-α-neuraminosyl)-(2-8)-O-(N-acetyl-α-neuraminosyl)-(2-3)-O-[O-(N-acetyl-α-neuraminosyl)-(2-3)-O-β-D-galactopyranosyl-(1-3)-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1-4)]-O-β-D-galactopyranosyl-(1-4)-D-glucose is a complex, defined oligosaccharide and a high-purity reference standard. This compound is critical for advanced research in glycobiology, virology, and immunology, serving as a precise molecular tool. It is primarily needed by pharmaceutical R&D teams, diagnostic developers, and academic research institutions focused on carbohydrate-protein interactions, pathogen adhesion mechanisms, and biomarker discovery.

Application

• Biochemical Research: Used as a high-purity standard and substrate in enzymatic studies of sialidases and sialyltransferases.
• Virology & Infectious Disease: Critical for investigating the binding mechanisms of influenza viruses, coronaviruses, and other pathogens that target sialylated glycans on host cells.
• Diagnostic Development: Serves as a key component in the development of assays and biosensors for detecting specific glycan-binding proteins or antibodies.
• Vaccine Research: Employed in the study of glycan-based epitopes for the design of novel conjugate vaccines and immunotherapies.
• Quality Control & Standardization: Acts as a reference material for the qualification and validation of analytical methods (HPLC, MS) in biopharmaceutical quality control labs.
• Cell Biology & Signaling: Used to study the role of complex glycans in cell-cell recognition, adhesion, and signal transduction processes.

Basic Information

Item	Detail
Product Name	O-(N-Acetyl-α-neuraminosyl)-(2-8)-O-(N-acetyl-α-neuraminosyl)-(2-3)-O-[O-(N-Acetyl-α-neuraminosyl)-(2-3)-O-β-D-galactopyranosyl-(1-3)-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1-4)]-O-β-D-galactopyranosyl-(1-4)-D-glucose
CAS No.	75663-36-4
Molecular Formula	C76H125N5O57
Molecular Weight	2020.79 g/mol
Synonyms	Disialyl Lacto-N-tetraose a; LST d; Sialyl Lewis x precursor; Neu5Acα2-8Neu5Acα2-3Galβ1-3(Neu5Acα2-3Galβ1-4)GlcNAcβ1-4Galβ1-4Glc; 6'-Sialyl-3'-sialyl-Lc4; IV6Neu5Ac,III6Neu5Ac-Lc4; Disialyllacto-N-tetraose a; A Trisialylated Oligosaccharide
EINECS	Contact for details

Quality Control

Every batch of our high-purity oligosaccharide standards undergoes rigorous analytical characterization to ensure identity, purity, and consistency. Our quality systems are designed to meet the exacting requirements of research and diagnostic applications. Comprehensive Certificates of Analysis (COA) detailing results from HPLC, MS, and NMR analyses are provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.