Description

n-Acetylneuraminic Acid is a fundamental sialic acid derivative and a key biochemical building block. Its role as a terminal sugar on glycoproteins and glycolipids makes it essential for modulating cellular recognition, immune response, and pathogen interactions. This high-purity compound is critical for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors, particularly for developing antiviral agents, vaccines, and advanced glycobiology research tools.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of antiviral drugs, including neuraminidase inhibitors like Zanamivir.
• Glycobiology Research: Essential substrate for studying sialyltransferases, neuraminidases, and other enzymes involved in glycosylation pathways.
• Diagnostic Reagent Production: Used in the manufacture of reagents for detecting influenza and other viruses that bind to sialic acid receptors.
• Nutraceutical & Cosmetic Ingredient: Investigated for use in functional foods and skincare products for its cell-signaling and moisturizing properties.
• Cell Culture & Media Supplement: Added to specialized cell culture media to influence cell surface glycosylation and improve protein production.
• Bioconjugation & Labeling: Serves as a target for chemical modification and labeling in the development of targeted therapeutics and imaging agents.

Basic Information

Product Name	n-Acetylneuraminic Acid
CAS No.	131-48-6
Molecular Formula	C11H19NO9
Molecular Weight	309.27 g/mol
Synonyms	N-Acetylneuraminic Acid; Neu5Ac; Sialic Acid (N-acetyl-); 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic Acid; NANA; Aceneuramic Acid; Lactaminic Acid; N-Acetyl-D-neuraminic Acid
EINECS	205-023-1

Quality Control

Our n-Acetylneuraminic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, specific rotation, and residual solvent analysis, to ensure it meets the stringent requirements for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	-32.0° to -36.0° (c=1 in H2O)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Microbial Limits	Meets standard for bioburden

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.