Description

6H-Imidazo[4,5-f]quinoline-6-carboxylic acid, 3-[(1R,3S)-3-carboxycyclohexyl]-2-[(R)-(5-fluoro-2-methoxyphenyl)hydroxymethyl]-3,7,8,9-tetrahydro-7-methyl-, 6-methyl ester, (7S)- is a sophisticated chiral intermediate of significant interest in advanced pharmaceutical synthesis. This compound matters for its role as a key building block in the development of novel therapeutic agents, particularly those targeting complex biological pathways. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of high-value, biologically active molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Development & Scale-up: Employed in the optimization and kilogram-scale production of candidate drugs during clinical trial material manufacturing.
• Bioconjugation & Probe Development: Potential utility in creating labeled compounds or conjugates for biochemical and diagnostic research due to its functionalized structure.

Basic Information

Product Name	6H-Imidazo[4,5-f]quinoline-6-carboxylic acid, 3-[(1R,3S)-3-carboxycyclohexyl]-2-[(R)-(5-fluoro-2-methoxyphenyl)hydroxymethyl]-3,7,8,9-tetrahydro-7-methyl-, 6-methyl ester, (7S)-
CAS No.	2407366-57-6
Molecular Formula	C29H31FN2O6
Molecular Weight	522.57 g/mol
Synonyms	(7S)-6-Methyl 3-[(1R,3S)-3-carboxycyclohexyl]-2-[(R)-(5-fluoro-2-methoxyphenyl)(hydroxy)methyl]-7-methyl-3,7,8,9-tetrahydro-6H-imidazo[4,5-f]quinoline-6-carboxylate; (7S)-6-Methyl ester of the specified imidazoquinoline carboxylic acid; UNII-Not Assigned; Advanced Pharmaceutical Intermediate 2407366-57-6; Chiral Imidazoquinoline Ester; Fluorinated Methoxy Phenyl Imidazoquinoline Derivative
EINECS	Contact for details

Quality Control

This high-purity intermediate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization including HPLC for purity and chiral purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical research. Certificates of Analysis (COA) with full analytical data are provided for each lot.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.