Description

(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-[(1R)-1-aminoethyl]oxan-2-yl]oxy-2-hydroxy-cyclohexyl]oxy-5-methyl-4-methylamino-oxane-3,5-diol is a complex, high-purity aminoglycoside derivative of significant interest in advanced pharmaceutical research and development. Its intricate stereochemistry and multiple functional groups make it a valuable chiral building block and intermediate for synthesizing novel therapeutic agents. This compound is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of antibiotics and other specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of novel aminoglycoside antibiotics and other complex therapeutic molecules.
• Biochemical Research: Used as a reference standard or probe in studies targeting bacterial ribosomes and understanding mechanisms of antibiotic action and resistance.
• Medicinal Chemistry: Employed as a sophisticated scaffold for structure-activity relationship (SAR) studies to develop new antimicrobial agents with improved efficacy and reduced toxicity.
• Process Development: Acts as a key intermediate for process chemists scaling up the production of target active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis, carbohydrate chemistry, and microbiology.

Basic Information

Product Name	(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-[(1R)-1-aminoethyl]oxan-2-yl]oxy-2-hydroxy-cyclohexyl]oxy-5-methyl-4-methylamino-oxane-3,5-diol
CAS No.	25876-11-3
Molecular Formula	C19H38N4O8
Molecular Weight	450.53 g/mol
Synonyms	4"-Deoxy-4"-methylaminoapramycin; 4"-Deoxy-4"-(methylamino)apramycin; Apramycin derivative; 6'-Deoxy-6'-methylaminoneomycin; Antibiotic XL-88; Paromamine derivative; Neomycin class aminoglycoside
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a cGMP-compliant quality management system suitable for supporting pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.