Description

8H-7,10-Methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid, 5-(1,1-diMethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-Methoxy-3,6-dioxo-, Methyl ester, (1aR,5S,8S,10R,22aR)- is a complex, high-purity synthetic intermediate with a defined stereochemistry. This compound is valued for its role as a key building block in advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of complex active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Process Chemistry Development: Serves as a key starting material or advanced intermediate in scaling up synthetic routes for clinical and commercial manufacturing.
• Fine Chemical Synthesis: Employed in the production of specialized, high-value compounds for research and diagnostic applications.
• Contract Research & Manufacturing (CRMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for cutting-edge organic synthesis and methodology development.

Basic Information

Item	Information
Product Name	8H-7,10-Methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid, 5-(1,1-diMethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-Methoxy-3,6-dioxo-, Methyl ester, (1aR,5S,8S,10R,22aR)-
CAS No.	1206524-84-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(1aR,5S,8S,10R,22aR)-5-(tert-Butyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid methyl ester; Methyl (1aR,5S,8S,10R,22aR)-5-(tert-butyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylate; CAS 1206524-84-6; Advanced pharmaceutical intermediate 1206524-84-6; Complex heterocyclic ester 1206524-84-6.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity intermediates. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing lot-specific results are available upon request. Our quality management system supports development under GMP-like conditions where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.