Description

IsoquinoliniuM, 2,2'-[(3-Methyl-1,5-pentanediyl)bis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-diMethoxyphenyl)Methyl]-1,2,3,4-tetrahydro-6,7-diMethoxy-2- Methyl-, (1R,1'R,2R,2'R)- is a complex, stereochemically defined bis-isoquinolinium derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a sophisticated chemical building block or pharmacological reference standard for investigating new therapeutic pathways, particularly in neuroscience and cardiology. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in the synthesis and study of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the multi-step synthesis of potential drug candidates targeting ion channels or G-protein-coupled receptors.
• Biochemical Research: Used as a high-purity reference standard or probe in pharmacological assays to study receptor binding affinity and functional activity.
• Medicinal Chemistry: Provides a structurally complex scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Process Chemistry Development: Acts as a critical intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions for clinical trial material production.
• Neuroscience Research: Investigated for potential interactions with neurological targets, given the structural motifs common to certain neuroactive compounds.
• Analytical Method Development: Employed as an analytical standard for developing and validating HPLC, LC-MS, or chiral separation methods.

Basic Information

Item	Details
Product Name	IsoquinoliniuM, 2,2'-[(3-Methyl-1,5-pentanediyl)bis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-diMethoxyphenyl)Methyl]-1,2,3,4-tetrahydro-6,7-diMethoxy-2- Methyl-, (1R,1'R,2R,2'R)-
CAS No.	1193104-79-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(1R,1'R,2R,2'R)-2,2'-[(3-Methyl-1,5-pentanediyl)bis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium; Bis-isoquinolinium derivative; 1193104-79-8; (R,R,R,R)-Isoquinolinium dimer; Tetrahydroisoquinolinium dimer; Chiral bis(isoquinolinium) compound; Dimethoxy phenylmethyl tetrahydroisoquinolinium derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specific results for each lot are available upon request. We adhere to a quality management system to ensure traceability and consistency for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccant use and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.