Description

3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-[4-[[[(1S)-2-Methoxy-1-Methyl-2-oxoethyl]amino]thioxoMethyl]-3-Methyl-1-piperazinyl]-4-oxo- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of critical importance for its role as a key building block in the synthesis of novel, potent antibacterial agents, particularly within the fluoroquinolone class. It is primarily required by pharmaceutical R&D laboratories and active pharmaceutical ingredient (API) manufacturers engaged in developing next-generation antibiotics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of advanced fluoroquinolone antibiotics.
• Antibacterial Drug Development: Used in R&D for creating new compounds targeting resistant bacterial strains.
• Chemical Synthesis Research: Serves as a complex scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Manufacturing: Integrated into the production process of final drug substances.
• Process Chemistry: Used in scale-up and optimization of synthetic routes for antibiotic production.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-[4-[[[(1S)-2-Methoxy-1-Methyl-2-oxoethyl]amino]thioxoMethyl]-3-Methyl-1-piperazinyl]-4-oxo-
CAS No.	1035086-11-3
Molecular Formula	C24H28FN4O6S
Molecular Weight	519.57 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-8-methoxy-7-[4-[[[(1S)-2-methoxy-1-methyl-2-oxoethyl]amino]thioxomethyl]-3-methyl-1-piperazinyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid; (1S)-1-Methyl-2-[[[4-(1-Cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinolinyl)-2-methyl-1-piperazinyl]thioxomethyl]amino]-2-oxoethyl methyl ester; A key intermediate for Sitafloxacin; Sitafloxacin intermediate; DU-6859a intermediate; Advanced fluoroquinolone intermediate.
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic acid intermediate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical synthesis. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.