Description

(R)-1-[(R)-2-(2''-Dicyclohexylphosphinophenyl)ferrocenyl]ethyldi-(bis-3,5-trifluoromethylphenyl)phosphine]-(N5-2,4-dimethylpentadienyl)(N-acetonitrile)ruthenium(II)]tetrafluoroborate is a highly sophisticated, chiral ruthenium-based organometallic complex designed for advanced asymmetric catalysis. Its value lies in its precise stereochemical control, enabling the synthesis of enantiomerically pure compounds critical for high-value chemical manufacturing. This product is essential for research and process development chemists in the pharmaceutical, agrochemical, and fine chemical industries, where it serves as a key catalyst for challenging hydrogenation and other transition metal-catalyzed reactions.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Chiral Ligand Precursor: The complex can serve as a source of its unique Josiphos-type ferrocenyl phosphine ligand for other catalytic systems.
• Process Chemistry Development: Used in R&D for scaling up enantioselective routes to active pharmaceutical ingredients (APIs) and agrochemicals.
• Academic & Industrial Research: A valuable tool for studying structure-activity relationships in chiral catalysis and developing new synthetic methodologies.
• Fine Chemical Synthesis: Enables the production of chiral flavors, fragrances, and advanced materials with high optical purity.

Basic Information

Product Name	(R)-1-[(R)-2-(2''-Dicyclohexylphosphinophenyl)ferrocenyl]ethyldi-(bis-3,5-trifluoromethylphenyl)phosphine]-(N5-2,4-dimethylpentadienyl)(N-acetonitrile)ruthenium(II)]tetrafluoroborate
CAS No.	1021494-98-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ru-(S)-BINAP derivative (chiral Ru complex); Chiral Ruthenium Josiphos Catalyst; [(R)-1-[(R)-2-(Dicyclohexylphosphino)ferrocenyl]ethylbis(3,5-bis(trifluoromethyl)phenyl)phosphine](2,4-dimethylpentadienyl)(acetonitrile)ruthenium(II) tetrafluoroborate; Asymmetric Hydrogenation Ruthenium Catalyst; Ru-(R)-Xyl-P-Phos related complex; Ferrocenylphosphine-Ruthenium Catalyst
EINECS	Contact for details

Quality Control

Every batch of this high-value catalyst is produced and handled under strict inert atmosphere conditions to preserve its catalytic activity. Our quality assurance includes rigorous analytical testing to confirm identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as assay (by NMR or HPLC), chiral purity, and residual solvent content. We adhere to cGMP principles where applicable for advanced intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and hygroscopic (moisture-sensitive), this material must be stored under an inert gas (argon or nitrogen) in a sealed vial or Schlenk flask. Recommended storage temperature is between 2°C and 8°C (refrigerated) for long-term stability. The container should be allowed to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 99.0% ee
Solvent Content (Residual)	≤ 2.0% (by NMR or GC)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.