Description

Ethyl 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylate is a high-purity, synthetically valuable pharmaceutical intermediate. This compound is a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly within the quinolone and naphthyridine antibiotic classes. It is essential for R&D laboratories and production facilities focused on developing and manufacturing next-generation antibacterial agents.

Application

• Key Intermediate for Antibiotic Synthesis: Serves as a core precursor in the production of novel quinolone-based antibacterial agents.
• Pharmaceutical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new therapeutic candidates.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in scaled-up synthesis processes for final API production under GMP conditions.
• Chemical Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control testing.
• Process Chemistry Optimization: Utilized in route scouting and process development to improve yield, purity, and cost-efficiency of target molecules.

Basic Information

Product Name	Ethyl 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylate
CAS No.	174726-87-5
Molecular Formula	C₁₄H₁₀ClN₃O₃S
Molecular Weight	335.76 g/mol
Synonyms	7-Chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid ethyl ester; Ethyl 7-chloro-1-(2-thiazolyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate; 1,8-Naphthyridine-3-carboxylic acid, 7-chloro-1,4-dihydro-4-oxo-1-2-thiazolyl-, ethyl ester; 174726-87-5; 7-Chloro-1-(thiazol-2-yl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our ethyl 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability, consistency, and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to protect the material from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.