Description

1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoquinoline, (8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-3-sulfooxy-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene is a complex, high-purity synthetic organic compound featuring a unique hybrid structure combining isoquinoline and steroidal phenanthrene motifs. This compound is of significant interest for its potential as a key intermediate or reference standard in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for exploring novel therapeutic pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting steroid hormone receptors or neurological pathways.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis (HPLC, LC-MS).
• Biochemical Research: Employed in academic and industrial research to study enzyme inhibition, receptor binding assays, and structure-activity relationships (SAR).
• Process Chemistry: Acts as a starting material or advanced intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Library Synthesis: Utilized in medicinal chemistry for the generation of focused compound libraries aimed at drug discovery programs.

Basic Information

Product Name	1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoquinoline, (8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-3-sulfooxy-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene
CAS No.	101831-49-6
Molecular Formula	C₃₀H₃₅NO₈S
Molecular Weight	569.67 g/mol
Synonyms	1-[(3,4-Dimethoxybenzyl)-6,7-dimethoxyisoquinoline steroid conjugate; 3-Sulfooxyestra-1,3,5(10)-trien-17-one derivative; 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxyisoquinoline-17-oxo-estrane-3-sulfate; Steroidal isoquinoline sulfate ester; CAS 101831-49-6; (8R,9S,10R,13S,14S)-3-(Sulfooxy)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydro-6H-cyclopenta[a]phenanthren-6-yl 3,4-dimethoxybenzyl-6,7-dimethoxyisoquinoline
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to rigorous quality standards to ensure batch-to-batch consistency and reliability for your critical research and development work. Identity, purity, and impurity profiles are verified using advanced analytical techniques including HPLC, LC-MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment. We support development under quality systems suitable for cGMP compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.