Description

3-(2-(Trifluoromethyl)Benzyl)Azetidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique azetidine scaffold substituted with a trifluoromethylbenzyl group. This compound is valued for its role as a critical building block in modern medicinal chemistry, enabling the synthesis of novel bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting G-protein-coupled receptors (GPCRs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a building block for creating tool compounds and molecular probes to study biological pathways.
• Agrochemical Development: Potential intermediate in the research and synthesis of new crop protection agents and pesticides.
• Material Science: Investigated for incorporation into specialty polymers and advanced organic materials.

Basic Information

Product Name	3-(2-(Trifluoromethyl)Benzyl)Azetidine Hydrochloride
CAS No.	960492-85-7
Molecular Formula	C11H12F3N·HCl
Molecular Weight	251.67 g/mol (Free base: 215.22 g/mol)
Synonyms	3-[(2-(Trifluoromethyl)phenyl)methyl]azetidine hydrochloride; 1-(2-(Trifluoromethyl)benzyl)azetidin-3-amine hydrochloride; Azetidine, 3-[[2-(trifluoromethyl)phenyl]methyl]-, hydrochloride (1:1); 3-(2-(Trifluoromethyl)benzyl)azetidine HCl; 960492-85-7
EINECS	Contact for details

Quality Control

Our 3-(2-(Trifluoromethyl)Benzyl)Azetidine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.