Description

trans-4-(Dimethylamino)-3-Pyrrolidinol dihydrochloride is a high-purity, salt-form intermediate of significant value in advanced organic synthesis. Its pyrrolidine scaffold, functionalized with dimethylamino and hydroxyl groups, makes it a versatile chiral building block for constructing complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high-purity intermediates.
• Academic and R&D Laboratories: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	trans-4-(Dimethylamino)-3-Pyrrolidinol dihydrochloride
CAS No.	960289-61-6
Molecular Formula	C6H14N2O • 2HCl
Molecular Weight	215.11 g/mol
Synonyms	trans-4-(Dimethylamino)-3-pyrrolidinol hydrochloride; (3R,4R)-4-(Dimethylamino)pyrrolidin-3-ol dihydrochloride; (3S,4S)-4-(Dimethylamino)pyrrolidin-3-ol dihydrochloride; 4-(N,N-Dimethylamino)-3-hydroxy-pyrrolidine dihydrochloride; 3-Pyrrolidinol, 4-(dimethylamino)-, hydrochloride (1:2), trans-; 960289-61-6; 4-Dimethylamino-3-hydroxypyrrolidine dihydrochloride
EINECS	Contact for details

Quality Control

Our trans-4-(Dimethylamino)-3-Pyrrolidinol dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.