Description

2-(2,5-Difluorophenyl)Pyrimidine-5-Carbaldehyde is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a difluorinated phenyl ring with a pyrimidine carbaldehyde moiety, making it a versatile precursor for constructing complex pharmacophores. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluorophenyl and pyrimidine groups.
• Material Science Research: Serves as a building block for organic electronic materials, such as ligands for OLEDs or molecular sensors.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds or probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-(2,5-Difluorophenyl)Pyrimidine-5-Carbaldehyde
CAS No.	960198-49-6
Molecular Formula	C11H6F2N2O
Molecular Weight	220.18 g/mol
Synonyms	5-Pyrimidinecarboxaldehyde, 2-(2,5-difluorophenyl)-; 2-(2,5-Difluorophenyl)-5-pyrimidinecarboxaldehyde; 2-(2,5-Difluorophenyl)pyrimidine-5-carboxaldehyde; 2-(2,5-Difluorophenyl)-5-formylpyrimidine; 960198-49-6; 2-(2,5-Difluorophenyl)-5-pyrimidinecarbaldehyde; 5-Formyl-2-(2,5-difluorophenyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 2-(2,5-Difluorophenyl)Pyrimidine-5-Carbaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with the standards expected by pharmaceutical and fine chemical industries, ensuring reliable supply and technical support for your projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.