Description

(8α,9S)-9-Amino-Cinchonan-6'-Ol CAS NO 960050-59-3 is a high-purity, chiral cinchona alkaloid derivative, serving as a critical building block and chiral auxiliary in advanced organic synthesis. Its primary value lies in its ability to impart stereoselectivity in catalytic and stoichiometric reactions, enabling the production of enantiomerically pure compounds. This product is essential for research and development laboratories, as well as production facilities in the pharmaceutical, agrochemical, and fine chemical industries, where precise stereochemical control is paramount.

Application

• Asymmetric Synthesis: Employed as a chiral ligand or organocatalyst in enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions.
• Pharmaceutical Intermediates: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry, particularly for antimalarial and antiarrhythmic drug candidates.
• Chiral Resolution: Used in the preparation of chiral stationary phases for HPLC or as a resolving agent for the separation of racemic mixtures.
• Fine Chemical Production: Facilitates the manufacture of complex, high-value specialty chemicals with defined three-dimensional structures.
• Academic & Industrial R&D: A valuable tool for methodological development in catalysis and synthetic organic chemistry research.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.

Basic Information

Product Name	(8α,9S)-9-Amino-Cinchonan-6'-Ol
CAS No.	960050-59-3
Molecular Formula	C19H24N2O
Molecular Weight	296.41 g/mol
Synonyms	9-Aminocinchonan-6-ol; (8α,9S)-9-Aminocinchonan-6'-ol; 9-Amino-6'-hydroxycinchonane; 9-Aminocinchonan-6-ol (8α,9S)-; Cinchonan-6'-ol, 9-amino-, (8α,9S)-; 9-Aminodihydroquinine; A key intermediate for chiral ligands.
EINECS	Contact for details

Quality Control

Every batch of (8α,9S)-9-Amino-Cinchonan-6'-Ol is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and cGMP-grade production. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), chiral purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.