Description

n-Nitrosopiperidine-D10 is a deuterated isotopologue of n-nitrosopiperidine, a stable-labeled compound essential for advanced analytical research. This high-purity material serves as a critical internal standard for the accurate quantification and trace analysis of nitrosamine impurities in pharmaceuticals and other complex matrices. It is primarily utilized by analytical laboratories, research institutions, and quality control departments in the pharmaceutical, agrochemical, and environmental testing industries to ensure product safety and regulatory compliance.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis of nitrosamine impurities in active pharmaceutical ingredients (APIs) and finished drug products.
• Quantitative reference material in method development and validation for nitrosamine detection, supporting compliance with regulatory guidelines (e.g., FDA, EMA).
• Metabolic and pharmacokinetic tracer studies in biomedical and toxicological research.
• Calibration standard for high-precision analytical instrumentation in quality control laboratories.
• Research chemical for studying the environmental fate and degradation pathways of nitrosamines.
• Use in stable isotope dilution assays (SIDA) to achieve superior accuracy and precision in complex sample analysis.

Basic Information

Product Name	n-Nitrosopiperidine-D10
CAS No.	960049-21-2
Molecular Formula	C5D10N2O
Molecular Weight	130.20 g/mol
Synonyms	Piperidine-D10, 1-nitroso-; Deuterated N-Nitrosopiperidine; N-Nitrosopiperidine-d10; 1-Nitrosopiperidine-d10; N-NP-d10; NDMA-d10 (common class reference); Perdeuterated N-nitrosopiperidine; [2H10]-N-Nitrosopiperidine
EINECS	Contact for details

Quality Control

Our n-Nitrosopiperidine-D10 is manufactured under strict quality systems to ensure the high purity and isotopic enrichment required for sensitive analytical applications. Each batch undergoes comprehensive analysis, including NMR, HPLC, and MS, to confirm chemical and isotopic purity. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific customer or pharmacopeial method requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Content)	≥ 98.0 atom % D
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.