Description

S-2-n-Boc-Propane-1,2-Diamine-Hcl is a high-purity, protected diamine derivative used as a critical chiral building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures with precise stereochemistry, enabling the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for peptide mimetics, linker molecules, and catalyst ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, kinase inhibitors, and other small molecule therapeutics.
• Peptidomimetic Chemistry: Used to introduce a chiral diamine backbone in the design of peptide analogs and macrocyclic compounds.
• Linker and Spacer Unit: Employed in medicinal chemistry for constructing drug conjugates and bifunctional molecules due to its protected amine groups.
• Catalyst and Ligand Synthesis: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Agrochemical Research: Utilized in the development of novel herbicides and fungicides with specific stereochemical requirements.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic synthesis and chemical biology.

Basic Information

Product Name	S-2-n-Boc-Propane-1,2-Diamine-Hcl
CAS No.	959833-70-6
Molecular Formula	C8H19ClN2O2
Molecular Weight	210.70 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)-1,2-diaminopropane hydrochloride; (S)-1,2-Diaminopropane, N2-Boc, hydrochloride; (S)-N-Boc-1,2-diaminopropane hydrochloride; (S)-2-(Boc-amino)-1,2-propanediamine hydrochloride; (S)-1,2-Propanediamine, N2-[(1,1-dimethylethoxy)carbonyl]-, hydrochloride (1:1); Boc-Dap-OH.HCl; (S)-N2-Boc-1,2-diaminopropane hydrochloride; tert-Butyl (S)-(1,2-diaminopropan-2-yl)carbamate hydrochloride
EINECS	Contact for details

Quality Control

Our S-2-n-Boc-Propane-1,2-Diamine-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting standards for research and development use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.