Description

tert-Butyl 1,5-Naphthyridin-3-Ylcarbamate is a high-purity, protected carbamate derivative of the 1,5-naphthyridine heterocyclic system. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, particularly for the development of active pharmaceutical ingredients (APIs). It is essential for research and production in medicinal chemistry, where its structure is utilized to construct complex molecules with potential therapeutic activity. The product is supplied under stringent quality control to ensure consistency for demanding applications.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis: Employed in multi-step synthetic routes to introduce the protected 1,5-naphthyridin-3-ylcarbamate moiety into more complex molecular architectures.
• Agrochemical Development: Potential intermediate in the synthesis of advanced crop protection agents and pesticides.
• Material Science: Can be investigated as a monomer or precursor for functional organic materials and ligands in coordination chemistry.

Basic Information

Product Name	tert-Butyl 1,5-Naphthyridin-3-Ylcarbamate
CAS No.	959617-73-3
Molecular Formula	C14H17N3O2
Molecular Weight	259.31 g/mol
Synonyms	1,5-Naphthyridin-3-amine, N-[(1,1-dimethylethoxy)carbonyl]-; tert-Butyl 1,5-naphthyridin-3-ylcarbamate; 3-((tert-Butoxycarbonyl)amino)-1,5-naphthyridine; Boc-1,5-naphthyridin-3-ylamine; N-Boc-3-amino-1,5-naphthyridine; 1,5-Naphthyridin-3-yl-carbamic acid tert-butyl ester; 959617-73-3; tert-Butyl (1,5-naphthyridin-3-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 1,5-Naphthyridin-3-Ylcarbamate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards required for GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.