Description

Quinazoline, 4-Chloro-7-Iodo-2-(Trifluoromethyl)- is a high-value, multi-functional halogenated heterocyclic building block. This compound is specifically engineered to serve as a critical intermediate in advanced pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, anticancer agents, and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the quinazoline core.
• Material Science Precursor: Serves as a building block for creating specialized organic ligands, fluorinated polymers, or advanced organic electronic materials.
• Chemical Biology Probe Development: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a tagged molecule in biochemical assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring this specific halogenated quinazoline scaffold.

Basic Information

Product Name	Quinazoline, 4-Chloro-7-Iodo-2-(Trifluoromethyl)-
CAS No.	959237-77-5
Molecular Formula	C9H3ClF3IN2
Molecular Weight	358.48 g/mol
Synonyms	4-Chloro-7-iodo-2-(trifluoromethyl)quinazoline; 2-(Trifluoromethyl)-4-chloro-7-iodoquinazoline; 4-Chloro-7-iodo-2-trifluoromethylquinazoline; Quinazoline, 4-chloro-7-iodo-2-(trifluoromethyl)-; 959237-77-5; 4-Chloro-7-iodo-2-(trifluoromethyl)quinazoline; 7-Iodo-4-chloro-2-(trifluoromethyl)quinazoline
EINECS	Contact for details

Quality Control

Our Quinazoline, 4-Chloro-7-Iodo-2-(Trifluoromethyl)- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material at 2-8°C under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.