Description

2,4-Dichloro-7-Bromoquinazoline is a high-value halogenated quinazoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring reactive chlorine and bromine atoms at strategic positions, makes it an indispensable building block for constructing complex heterocyclic systems. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of tyrosine kinase inhibitors (TKIs) and other targeted cancer therapeutics.
• Agrochemical Research: Building block for developing new fungicides and herbicides with novel modes of action.
• Material Science: Used in the creation of organic electronic materials and photoactive compounds.
• Chemical Biology: Serves as a scaffold for designing enzyme inhibitors and molecular probes in drug discovery.
• Custom Synthesis: Employed in contract research and manufacturing (CRAM) for bespoke chemical library production.
• Academic Research: Fundamental reagent for methodological studies in cross-coupling and nucleophilic substitution reactions.

Basic Information

Product Name	2,4-Dichloro-7-Bromoquinazoline
CAS No.	959237-68-4
Molecular Formula	C8H3BrCl2N2
Molecular Weight	278.93 g/mol
Synonyms	7-Bromo-2,4-dichloroquinazoline; 2,4-Dichloro-7-bromoquinazoline; Quinazoline, 7-bromo-2,4-dichloro-; 959237-68-4; 7-Bromo-2,4-dichloro-quinazoline; 2,4-Dichloro-7-bromo-quinazoline
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-7-Bromoquinazoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.