Description

2-Methyl-2-(3-(Trifluoromethyl)Phenyl)Propan-1-Amine Hydrochloride is a high-purity, functionalized amine hydrochloride salt, a key building block in advanced organic synthesis. Its value lies in the unique combination of a sterically hindered amine and a trifluoromethylphenyl group, which are critical for modulating the physicochemical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of central nervous system (CNS) agents and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioavailability and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and functional materials that require specific amine functionalities.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of chemical probes for target identification.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Methyl-2-(3-(Trifluoromethyl)Phenyl)Propan-1-Amine Hydrochloride
CAS No.	959139-62-9
Molecular Formula	C11H14F3N·HCl
Molecular Weight	253.69 g/mol (Free base: 217.23 g/mol)
Synonyms	1-Propanamine, 2-methyl-2-[3-(trifluoromethyl)phenyl]-, hydrochloride (1:1); 2-Methyl-2-[3-(trifluoromethyl)phenyl]propan-1-amine hydrochloride; α,α-Dimethyl-3-(trifluoromethyl)benzylamine hydrochloride; 3-(Trifluoromethyl)benzenemethanamine, α,α-dimethyl-, hydrochloride; 2-Methyl-2-(3-trifluoromethylphenyl)propylamine HCl; 959139-62-9; (3-(Trifluoromethyl)phenyl)neopentylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-(3-(Trifluoromethyl)Phenyl)Propan-1-Amine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in GMP-intermediate synthesis and research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC Area %)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.