Description

2H-Pyrrole-5-Acetonitrile, 3,4-Dihydro--α--[5-(1-Hydroxy-1-Methylethyl)-2-Pyrrolidinylidene]-, (-α-Z)- is a specialized pyrrole-based nitrile derivative that serves as a high-value synthetic intermediate. Its complex, functionalized structure makes it a critical building block for constructing advanced molecular architectures in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, particularly in the areas of medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing complex heterocyclic cores.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its pyrrolidine scaffold for bioactivity.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex nitrogen-containing heterocycles due to its reactive nitrile and pyrrolidinylidene groups.
• Material Science Research: Potential monomer or precursor for functional polymers and advanced organic materials with specific electronic or binding properties.
• Academic & Institutional R&D: Utilized in universities and research institutes for methodological studies and exploring new chemical reactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical and chemical industries in their development pipelines.

Basic Information

Product Name	2H-Pyrrole-5-Acetonitrile, 3,4-Dihydro--α--[5-(1-Hydroxy-1-Methylethyl)-2-Pyrrolidinylidene]-, (-α-Z)-
CAS No.	959035-65-5
Molecular Formula	C11H15N3O
Molecular Weight	205.26 g/mol
Synonyms	(-α-Z)-3,4-Dihydro-α-[5-(1-hydroxy-1-methylethyl)-2-pyrrolidinylidene]-2H-pyrrole-5-acetonitrile; (Z)-α-(5-(2-Hydroxypropan-2-yl)-3,4-dihydro-2H-pyrrol-2-ylidene)-1H-pyrrole-2-acetonitrile; 959035-65-5; (Z)-2-(2-(5-(2-Hydroxypropan-2-yl)-3,4-dihydro-2H-pyrrol-2-ylidene)-1H-pyrrol-5-yl)acetonitrile; Pyrrole-5-acetonitrile, 3,4-dihydro-α-[5-(1-hydroxy-1-methylethyl)-2-pyrrolidinylidene]-, (αZ)-; A high-value pyrrole nitrile intermediate.
EINECS	Contact for details

Quality Control

Our production of 2H-Pyrrole-5-Acetonitrile, 3,4-Dihydro--α--[5-(1-Hydroxy-1-Methylethyl)-2-Pyrrolidinylidene]-, (-α-Z)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment. We support our clients' regulatory needs and can supply material suitable for research and development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C (refrigerated). Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.