Description

5-(Trifluoromethyl)Quinoline-7-Carboxylic Acid CAS NO 959035-11-1 is a high-value, multi-functional heterocyclic building block characterized by its quinoline core and trifluoromethyl substituent. This compound is essential for medicinal chemistry research and development, offering a versatile scaffold for creating novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical, agrochemical, and advanced material research organizations for its role in synthesizing compounds with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in oncology, antiviral, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent tags or molecular probes for studying biological processes.
• Catalyst Ligand Development: Acts as a starting material for creating novel chiral or achiral ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring specialized fluorinated quinoline derivatives.

Basic Information

Product Name	5-(Trifluoromethyl)Quinoline-7-Carboxylic Acid
CAS No.	959035-11-1
Molecular Formula	C11H6F3NO2
Molecular Weight	241.17 g/mol
Synonyms	5-(Trifluoromethyl)-7-quinolinecarboxylic acid; 7-Quinolinecarboxylic acid, 5-(trifluoromethyl)-; 5-Trifluoromethylquinoline-7-carboxylic acid; Quinoline-7-carboxylic acid, 5-(trifluoromethyl)-; 959035-11-1; 5-CF3-Quinoline-7-COOH
EINECS	Contact for details

Quality Control

Our production of 5-(Trifluoromethyl)Quinoline-7-Carboxylic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.