Description

5-Bromo-Quinazoline is a versatile and high-value brominated heterocyclic building block essential for advanced organic synthesis. Its core quinazoline scaffold, functionalized with a reactive bromine atom, makes it a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on kinase inhibitors, anticancer agents, and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, particularly kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging its heterocyclic structure.
• Chemical Biology: Serves as a versatile scaffold for creating chemical probes and tool compounds to study biological pathways and protein function.
• Material Science: Potential building block for advanced organic electronic materials due to its electron-deficient quinazoline core.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Bromo-Quinazoline
CAS No.	958452-00-1
Molecular Formula	C8H5BrN2
Molecular Weight	209.04 g/mol
Synonyms	5-Bromoquinazoline; Quinazoline, 5-bromo-; 958452-00-1; 5-Br-Quinazoline
EINECS	Contact for details

Quality Control

Our 5-Bromo-Quinazoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (by HPLC), identity confirmation (by IR and NMR), and impurity profiles. Our quality system is designed to support cGMP compliance for advanced intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.