Description

Ethyl 7-Bromo-1,5-naphthyridine-3-carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive bromine and ester functional groups, which enable precise molecular construction and diversification. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active naphthyridine derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for creating specialized organic ligands, dyes, and functional polymers.
• Academic & R&D: Employed in medicinal chemistry programs and methodological studies for cross-coupling reactions and heterocycle functionalization.
• Chemical Synthesis: The bromine atom facilitates Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions, while the ester group allows for hydrolysis or transesterification.

Basic Information

Product Name	Ethyl 7-Bromo-1,5-Naphthyridine-3-Carboxylate
CAS No.	958334-48-0
Molecular Formula	C11H9BrN2O2
Molecular Weight	281.11 g/mol
Synonyms	7-Bromo-1,5-naphthyridine-3-carboxylic acid ethyl ester; Ethyl 7-bromo-1,5-naphthyridine-3-carboxylate; 1,5-Naphthyridine-3-carboxylic acid, 7-bromo-, ethyl ester; 958334-48-0; 7-Bromo-1,5-naphthyridine-3-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 7-Bromo-1,5-naphthyridine-3-carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.