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R-3,3'-Bis(Triphenylsilyl)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Bi-2-Naphthyl Phosphate CAS NO 957790-94-2


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CAS No.:957790-94-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

R-3,3'-Bis(Triphenylsilyl)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Bi-2-Naphthyl Phosphate is a sophisticated chiral organophosphorus compound, valued for its role as a highly effective ligand and catalyst in asymmetric synthesis. Its unique sterically hindered, binaphthyl-based structure provides exceptional enantioselectivity and stability under demanding reaction conditions. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, where it is used to create high-value, optically pure intermediates for active pharmaceutical ingredients (APIs) and advanced materials.

Application

  • Asymmetric Catalysis: Serves as a privileged chiral ligand for transition metal-catalyzed reactions, including hydrogenation, cross-coupling, and C-H activation.
  • Pharmaceutical Intermediate Synthesis: Critical for the enantioselective construction of complex molecular architectures in API development.
  • Fine Chemical Production: Enables the synthesis of high-purity, single-enantiomer compounds for agrochemicals, flavors, and fragrances.
  • Material Science Research: Used in the development of chiral polymers and advanced organic frameworks with specific optical properties.
  • Academic & Industrial R&D: A key reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name R-3,3'-Bis(Triphenylsilyl)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Bi-2-Naphthyl Phosphate
CAS No. 957790-94-2
Molecular Formula C70H62O4P2Si2
Molecular Weight 1085.37 g/mol
Synonyms (R)-3,3'-Bis(triphenylsilyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthyl phosphate; (R)-H8-BINOL-3,3'-diyl bis(diphenylphosphate); (R)-Octahydrobinaphthol bis(triphenylsilyl) phosphate; BINAP derivative phosphate ligand; Chiral binaphthyl phosphate ligand; Asymmetric synthesis ligand CAS 957790-94-2
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Quality Control

Every batch of R-3,3'-Bis(Triphenylsilyl)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Bi-2-Naphthyl Phosphate is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and chiral analysis, to ensure high chemical and enantiomeric purity suitable for sensitive catalytic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with each shipment to guarantee batch-to-batch consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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