Description

(3Ar,4S,9Bs)-Ethyl 8-Bromo-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinoline-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex, stereochemically defined polycyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly those targeting the central nervous system. It is primarily sought after by R&D laboratories and pharmaceutical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, especially in neurological and psychiatric disorder research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the biological activity of quinoline-based compounds.
• Process Development: Serves as a critical intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Academic & Contract Research: Employed in university and CRO settings for exploratory synthesis and the development of new synthetic methodologies.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	(3Ar,4S,9Bs)-Ethyl 8-Bromo-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinoline-4-Carboxylate
CAS No.	957559-59-0
Molecular Formula	C15H16BrNO2
Molecular Weight	322.20 g/mol
Synonyms	Ethyl 8-bromo-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylate; 8-Bromo-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid ethyl ester; (3aR,4S,9bS)-Ethyl 8-bromo-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylate; 957559-59-0; UNII-4V9K8Q3G2P; 4V9K8Q3G2P; SCHEMBL2184971; AKOS040759977
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development and commercial projects with material produced under quality-controlled or cGMP-compliant protocols as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.