Description

n-Methyl 2-Bromoaniline, Hcl CAS NO 957120-69-3 is a halogenated aniline derivative, specifically the hydrochloride salt of N-methyl-2-bromoaniline, serving as a versatile and high-purity organic building block. This compound is critical for facilitating complex molecular synthesis, offering a reactive aromatic amine group protected in a stable salt form for precise chemical transformations. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the bromine and amine functionalities allow for further derivatization.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as a starting material for synthesizing complex azo dyes and organic pigments due to its aromatic amine structure.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed cross-coupling reactions, such as Buchwald-Hartwig amination, for constructing carbon-nitrogen bonds.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, library synthesis, and exploring new synthetic pathways.

Basic Information

Product Name	n-Methyl 2-Bromoaniline, Hcl
CAS No.	957120-69-3
Molecular Formula	C7H9BrN•HCl
Molecular Weight	236.52 g/mol
Synonyms	2-Bromo-N-methylaniline hydrochloride; N-Methyl-2-bromoaniline hydrochloride; 1-(2-Bromophenyl)-N-methylmethanamine hydrochloride; Benzenamine, 2-bromo-N-methyl-, hydrochloride; 2-Bromo-N-methylbenzenamine hydrochloride; N-Methyl-o-bromoaniline HCl; o-Bromo-N-methylaniline hydrochloride
EINECS	Contact for details

Quality Control

Our n-Methyl 2-Bromoaniline, Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.