Description

tert-Butyl 2-Bromo-5-Methoxybenzoate is a high-purity organic building block and synthetic intermediate of significant importance in advanced chemical synthesis. Its value lies in its versatile bromo and ester functional groups, which allow for selective transformations and incorporation into more complex molecular architectures. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Used in research and development for constructing advanced herbicide and fungicide molecules, leveraging the methoxy and bromo substituents for bioactivity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands and organometallic catalysts used in cross-coupling reactions and asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers where its aromatic core and substituents modify electronic and physical properties.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional laboratories for methodological studies in organic chemistry, including new reaction development and mechanistic investigations.

Basic Information

Product Name	tert-Butyl 2-Bromo-5-Methoxybenzoate
CAS No.	957063-12-6
Molecular Formula	C12H15BrO3
Molecular Weight	287.15 g/mol
Synonyms	2-Bromo-5-methoxybenzoic acid tert-butyl ester; Benzoic acid, 2-bromo-5-methoxy-, 1,1-dimethylethyl ester; tert-Butyl 2-bromo-5-methoxybenzoate; 1,1-Dimethylethyl 2-bromo-5-methoxybenzoate; 2-Bromo-5-methoxy-benzoic acid tert-butyl ester; t-Butyl 2-bromo-5-methoxybenzoate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Bromo-5-Methoxybenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.