Description

(S)-3-(1-(Furan-2-Ylmethyl)-2,5-Dioxoimidazolidin-4-Yl)Propanoic Acid is a high-purity chiral intermediate featuring a fused imidazolidinedione (hydantoin) and furan ring system. This compound is of significant value for its role as a sophisticated building block in the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly for creating novel peptidomimetics and enzyme inhibitors. The CAS number for this compound is 957042-67-0.

Application

This specialized chiral intermediate serves as a critical component in advanced organic synthesis across several high-value sectors:

• Pharmaceutical Research & Development: As a key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting protease inhibition or receptor modulation.
• Peptidomimetic Drug Design: Its hydantoin core and chiral center make it an ideal scaffold for constructing non-peptide analogs that mimic the structure and function of natural peptides, improving metabolic stability.
• Chemical Biology & Proteomics: Used in the development of activity-based probes and affinity tags to study enzyme function and protein-protein interactions.
• Asymmetric Synthesis: Employed as a chiral auxiliary or template in stereoselective reactions to induce the formation of new chiral centers with high enantiomeric purity.
• Agrochemical Intermediate: Potential use in the synthesis of advanced, chiral active ingredients for crop protection products.

Basic Information

Product Name	(S)-3-(1-(Furan-2-Ylmethyl)-2,5-Dioxoimidazolidin-4-Yl)Propanoic Acid
CAS No.	957042-67-0
Molecular Formula	C11H12N2O5
Molecular Weight	252.23 g/mol
Synonyms	(S)-3-[1-(2-Furylmethyl)-2,5-dioxo-4-imidazolidinyl]propanoic Acid; (4S)-3-(Furan-2-ylmethyl)-2,5-dioxo-4-imidazolidinepropanoic Acid; (S)-1-(Furan-2-ylmethyl)hydantoin-3-propionic Acid; (S)-3-(1-(2-Furanylmethyl)-2,5-dioxo-4-imidazolidinyl)propanoic Acid; Furan-2-ylmethyl-L-hydantoinpropionic Acid; 957042-67-0; (S)-Hydantoin Furan Propionic Acid Derivative
EINECS	Contact for details

Quality Control

Our production of (S)-3-(1-(Furan-2-Ylmethyl)-2,5-Dioxoimidazolidin-4-Yl)Propanoic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral HPLC to confirm enantiomeric excess (ee) and standard purity assays. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are provided with every shipment. We support development and cGMP manufacturing needs with appropriate documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of atmospheric moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.