Description

(1S,2R,3S,4R)-4-Aminocyclopentane-1,2,3-Triol Hydrochloride is a high-purity, stereochemically defined aminocyclitol derivative supplied as a hydrochloride salt. This compound serves as a critical chiral building block and intermediate in advanced pharmaceutical synthesis, enabling the development of novel therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of glycosidase inhibitors, antiviral agents, and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral and metabolic disease research.
• Glycosidase Inhibitor Development: Core scaffold for designing and testing new inhibitors targeting specific carbohydrate-processing enzymes.
• Chemical Biology Research: Used as a probe or precursor in studying enzyme mechanisms and carbohydrate-protein interactions.
• Process Chemistry & Scale-up: Serves as a starting material for the GMP-scale production of active pharmaceutical ingredients (APIs).
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	(1S,2R,3S,4R)-4-Aminocyclopentane-1,2,3-Triol Hydrochloride
CAS No.	956902-65-1
Molecular Formula	C5H12ClNO3
Molecular Weight	169.61 g/mol
Synonyms	(1S,2R,3S,4R)-4-Amino-1,2,3-cyclopentanetriol hydrochloride; 4-Amino-1,2,3-cyclopentanetriol, (1S,2R,3S,4R)-, hydrochloride; 1,2,3/4-Cyclopentanetetrol, 4-amino-, hydrochloride, (1S,2R,3S,4R)-; Aminocyclopentanetriol HCl; (1S,2R,3S,4R)-4-Aminocyclopentane-1,2,3-triol HCl
EINECS	Contact for details

Quality Control

Our (1S,2R,3S,4R)-4-Aminocyclopentane-1,2,3-Triol Hydrochloride is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed HPLC, NMR, and optical rotation data are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.