Description

1-Tosyl-1H-Pyrrolo[2,3-B]Pyridine-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its functionalized heterocyclic core. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in oncology and kinase inhibitor research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile aldehyde functionality.
• Chemical Biology: Serves as a scaffold for developing chemical probes to study biological pathways and protein functions.
• Organic Synthesis: Employed in multi-step synthetic routes to construct complex nitrogen-containing heterocycles.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical R&D and scale-up activities.

Basic Information

Product Name	1-Tosyl-1H-Pyrrolo[2,3-B]Pyridine-3-Carbaldehyde
CAS No.	956716-93-1
Molecular Formula	C15H12N2O3S
Molecular Weight	300.33 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridine-3-carbaldehyde, 1-[(4-methylphenyl)sulfonyl]-; 1-Tosyl-7-azaindole-3-carboxaldehyde; 1-(p-Toluenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde; 1-Tosyl-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde; 7-Azaindole-3-carboxaldehyde, 1-tosyl-; 1-Tosyl-1H-7-azaindole-3-carbaldehyde; 956716-93-1; 1-Tosyl-7-aza-1H-indole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1-Tosyl-1H-Pyrrolo[2,3-B]Pyridine-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.