Description

8Beta,9Alpha-Dihydroxylindan-4(5),7(11)-Dien-8Alpha,12-Olide is a specialized sesquiterpene lactone derivative, identified by CAS NO 956707-04-3, valued for its unique fused indane-diene-olide structure. This compound serves as a critical advanced pharmaceutical intermediate and a versatile scaffold in organic synthesis for developing novel bioactive molecules. It is primarily sought by research institutions and fine chemical manufacturers engaged in medicinal chemistry, process development, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential therapeutic agents targeting inflammation and other biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Natural Product Synthesis: Serves as a synthetic precursor or analog for complex sesquiterpenoid natural products.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of high-value fine chemicals.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies due to its lactone functionality.
• Reference Standard: Sourced for analytical purposes, including method development and quality control in R&D laboratories.

Basic Information

Product Name	8Beta,9Alpha-Dihydroxylindan-4(5),7(11)-Dien-8Alpha,12-Olide
CAS No.	956707-04-3
Molecular Formula	C15H16O4
Molecular Weight	260.29 g/mol
Synonyms	8β,9α-Dihydroxyindan-4(5),7(11)-dien-8α,12-olide; (8R,9S)-8,9-Dihydroxy-4,7(11)-indandien-8,12-olide; Indandiene-olide derivative; Sesquiterpene lactone intermediate; 4,7(11)-Indandiene-8,12-olide, 8,9-dihydroxy-; 956707-04-3; 8β,9α-Dihydroxy-4,7(11)-indandien-8α,12-olide
EINECS	Contact for details

Quality Control

Our 8Beta,9Alpha-Dihydroxylindan-4(5),7(11)-Dien-8Alpha,12-Olide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and production standards. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.