Description

2-Chloro-5,7-Difluoroquinoline-3-Carbaldehyde is a high-purity, multi-functional quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its unique halogenated and formyl-substituted structure makes it an indispensable building block for constructing complex heterocyclic systems with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in developing kinase inhibitors, antimicrobial agents, and other bioactive molecules.
• Agrochemical Research: Used to construct complex heterocyclic cores for new-generation pesticides, herbicides, and fungicides.
• Material Science: Serves as a building block for creating functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Synthesis: Versatile electrophile and formyl donor for multi-step synthetic routes, including palladium-catalyzed cross-coupling reactions and condensation reactions.
• Fluorescent Probe Development: The quinoline scaffold can be utilized to develop new fluorescent dyes and sensors for analytical and diagnostic applications.

Basic Information

Product Name	2-Chloro-5,7-Difluoroquinoline-3-Carbaldehyde
CAS No.	956631-90-6
Molecular Formula	C₁₀H₄ClF₂NO
Molecular Weight	227.60 g/mol
Synonyms	2-Chloro-5,7-difluoroquinoline-3-carboxaldehyde; 3-Formyl-2-chloro-5,7-difluoroquinoline; 5,7-Difluoro-2-chloroquinoline-3-carbaldehyde; Quinoline-3-carbaldehyde, 2-chloro-5,7-difluoro-; 956631-90-6
EINECS	Contact for details

Quality Control

Our 2-Chloro-5,7-Difluoroquinoline-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere to prevent oxidation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.