Description

(2S)-2-[(5-Ethyl-8-Oxo-[1,3]Dioxolo[4,5-G]Quinoline-7-Carbonyl)Amino]-3-Methyl-Butanoic Acid is a high-purity, non-natural amino acid derivative featuring a complex quinoline-dioxole fused ring system. This compound serves as a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Bioconjugation & Probe Development: The carboxylic acid and amide functionalities allow for conjugation to peptides, proteins, or fluorescent tags for biochemical research.
• Chemical Biology Studies: Employed as a tool compound to investigate biological processes and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific, high-value compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(2S)-2-[(5-Ethyl-8-Oxo-[1,3]Dioxolo[4,5-G]Quinoline-7-Carbonyl)Amino]-3-Methyl-Butanoic Acid
CAS No.	956626-62-3
Molecular Formula	C20H22N2O6
Molecular Weight	386.40 g/mol
Synonyms	L-Valine, N-[(5-ethyl-8-oxo[1,3]dioxolo[4,5-g]quinolin-7-yl)carbonyl]-; (S)-2-((5-Ethyl-8-oxo-8H-[1,3]dioxolo[4,5-g]quinoline-7-carbonyl)amino)-3-methylbutanoic acid; 7-[[(2S)-1-Carboxy-2-methylpropyl]carbamoyl]-5-ethyl-8-oxo[1,3]dioxolo[4,5-g]quinoline; 5-Ethyl-8-oxo-8H-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid (2S)-2-amino-3-methylbutanoic acid (1:1); CAS 956626-62-3
EINECS	Contact for details

Quality Control

Our (2S)-2-[(5-Ethyl-8-Oxo-[1,3]Dioxolo[4,5-G]Quinoline-7-Carbonyl)Amino]-3-Methyl-Butanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and spectroscopic identification (IR, NMR). A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; ensure the container is kept sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.