Description

1-(Hydroxymethyl)Cyclobutane-1-Carbonitrile is a versatile cyclobutane-based nitrile derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring both a hydroxymethyl and a nitrile group on the same carbon atom, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the cyclobutane ring can impart unique biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties.
• Fine Chemical Production: Employed in multi-step syntheses of complex fragrance molecules, dyes, and other specialty chemicals.

Basic Information

Product Name	1-(Hydroxymethyl)Cyclobutane-1-Carbonitrile
CAS No.	956531-83-2
Molecular Formula	C6H9NO
Molecular Weight	111.14 g/mol
Synonyms	1-(Hydroxymethyl)cyclobutanecarbonitrile; (1-Cyano-1-cyclobutyl)methanol; 1-Cyano-1-(hydroxymethyl)cyclobutane; Cyclobutanecarbonitrile, 1-(hydroxymethyl)-; Hydroxymethylcyclobutanecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-(Hydroxymethyl)Cyclobutane-1-Carbonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP standards for pharmaceutical-grade material, ensuring traceability and reliability for critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.