Description

((3Ar,5R,6S,6Ar)-5-((tert-Butyldiphenylsilyloxy)Methyl)-2,2-Dimethyl-6-(Naphthalen-2-Ylmethoxy)-Dihydro-5H-Furo[3,2-D][1,3]Dioxol-5-Yl)Methanol CAS NO 956485-08-8 is a sophisticated, high-purity chiral intermediate featuring a protected diol and a naphthylmethyl ether group. This compound is of critical importance in advanced organic synthesis, particularly for constructing complex molecular architectures with precise stereochemistry. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the multi-step synthesis of complex drug candidates, especially in antiviral, anticancer, and anti-inflammatory research.
• Nucleoside/Nucleotide Analog Synthesis: Serves as a protected precursor for the synthesis of modified nucleosides and nucleotides used in medicinal chemistry and biochemistry.
• Glycosylation Chemistry: Utilized in the preparation of complex carbohydrate mimetics and glycoconjugates due to its protected furodioxolane structure.
• Asymmetric Synthesis: Employed as a chiral auxiliary or template to induce stereoselectivity in catalytic reactions for producing enantiomerically pure compounds.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production for target molecules.
• Academic & Industrial Research: A valuable reagent for exploring new synthetic methodologies and reaction pathways in organic chemistry.

Basic Information

Product Name	((3Ar,5R,6S,6Ar)-5-((tert-Butyldiphenylsilyloxy)Methyl)-2,2-Dimethyl-6-(Naphthalen-2-Ylmethoxy)-Dihydro-5H-Furo[3,2-D][1,3]Dioxol-5-Yl)Methanol
CAS No.	956485-08-8
Molecular Formula	C38H42O6Si
Molecular Weight	622.83 g/mol
Synonyms	(3aR,5R,6S,6aR)-5-[[(1,1-Dimethylethyl)diphenylsilyl]oxymethyl]-2,2-dimethyl-6-[(2-naphthalenylmethoxy)methyl]tetrahydrofuro[3,2-d][1,3]dioxol-5-ol; 5-((tert-Butyldiphenylsilyloxy)methyl)-2,2-dimethyl-6-(naphthalen-2-ylmethoxy)-5H-furo[3,2-d][1,3]dioxol-5-ylmethanol; TBDPS-Protected Diol Intermediate; Naphthylmethyl Ether Furodioxolane Methanol; Chiral Furo[3,2-d][1,3]dioxolane Derivative; 956485-08-8; CAS 956485-08-8
EINECS	Contact for details

Quality Control

Our ((3Ar,5R,6S,6Ar)-5-((tert-Butyldiphenylsilyloxy)Methyl)-2,2-Dimethyl-6-(Naphthalen-2-Ylmethoxy)-Dihydro-5H-Furo[3,2-D][1,3]Dioxol-5-Yl)Methanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.