Description

Spiro[Bicyclo[3.2.1]Octane-8,2'-[1,3]Dithiolane]-3-Carboxylic Acid CAS NO 956437-13-1 is a sophisticated spirocyclic organic compound featuring a carboxylic acid functional group integrated with a dithiolane moiety. This unique molecular architecture makes it a high-value intermediate for advanced organic synthesis, particularly in the development of novel pharmaceuticals and functional materials. It is primarily sought by research institutions and fine chemical manufacturers engaged in medicinal chemistry, ligand design, and the synthesis of complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its dithiolane and carboxylic acid functionalities.
• Advanced Material Research: Acts as a precursor for polymers and functional materials requiring rigid, spirocyclic backbones for enhanced thermal or mechanical properties.
• Agrochemical Development: Employed in the research and synthesis of new-generation herbicides and plant growth regulators.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms and biological pathways.
• Chiral Auxiliary/Synthon: Its complex, three-dimensional structure makes it a valuable chiral synthon in asymmetric synthesis.

Basic Information

Product Name	Spiro[Bicyclo[3.2.1]Octane-8,2'-[1,3]Dithiolane]-3-Carboxylic Acid
CAS No.	956437-13-1
Molecular Formula	C11H14O2S2
Molecular Weight	242.36 g/mol
Synonyms	Spiro(bicyclo[3.2.1]octane-8,2'-[1,3]dithiolane)-3-carboxylic acid; 3-Carboxyspiro(bicyclo[3.2.1]octane-8,2'-[1,3]dithiolane); 1,3-Dithiolane-2-carboxylic acid, 2-(3-bicyclo[3.2.1]octanyl)-, (1R,3S,5S,8R)-rel-; Spirocyclic dithiolane carboxylic acid; Bicyclo[3.2.1]octane-dithiolane-carboxylic acid spiro compound.
EINECS	Contact for details

Quality Control

Our production of Spiro[Bicyclo[3.2.1]Octane-8,2'-[1,3]Dithiolane]-3-Carboxylic Acid adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality system is designed to support cGMP requirements for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.