Description

4-[(3Ar,4S,9Bs)-6-Ethoxy-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinolin-4-Yl]Benzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex, stereochemically defined cyclopentaquinoline scaffold. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly those targeting central nervous system and inflammatory pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially for neurological and anti-inflammatory applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique fused ring system.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Academic & Institutional Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Pre-clinical Development: Utilized in the production of compounds for pharmacological screening and pre-clinical testing phases.

Basic Information

Product Name	4-[(3Ar,4S,9Bs)-6-Ethoxy-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinolin-4-Yl]Benzoic Acid
CAS No.	956189-58-5
Molecular Formula	C21H21NO3
Molecular Weight	335.40 g/mol
Synonyms	4-[(3aR,4S,9bS)-6-Ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoic acid; (3aR,4S,9bS)-4-(4-Carboxyphenyl)-6-ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline; 6-Ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-benzoic acid derivative; CAS 956189-58-5; Ethoxy Cyclopentaquinoline Benzoic Acid; ECPQBA; A selective intermediate for neuroactive compounds.
EINECS	Contact for details

Quality Control

Our production of 4-[(3Ar,4S,9Bs)-6-Ethoxy-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinolin-4-Yl]Benzoic Acid adheres to stringent quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.