Description

Florbetapir F 18 is a positron emission tomography (PET) imaging radiopharmaceutical agent. Its core value proposition lies in its high-affinity binding to β-amyloid plaques in the brain, enabling non-invasive detection and assessment. This product is essential for research institutions, pharmaceutical developers, and clinical diagnostic centers focused on neurodegenerative diseases, particularly Alzheimer's disease.

Application

• Clinical PET Imaging: For the detection and estimation of β-amyloid neuritic plaque density in the brains of adult patients with cognitive impairment.
• Alzheimer's Disease Research: Used as a critical tool in clinical trials to evaluate the efficacy of novel therapeutic agents targeting amyloid pathology.
• Differential Diagnosis: Aiding in the differential diagnosis of cognitive decline by distinguishing Alzheimer's disease from other forms of dementia.
• Biomarker Validation Studies: Serving as a reference standard in studies aimed at validating new biomarkers for neurodegenerative conditions.
• Radiopharmaceutical Development: Acting as a key intermediate or reference compound in the synthesis and quality control of novel F-18 labeled tracers.

Basic Information

Product Name	Florbetapir F 18
CAS No.	956103-76-7
Molecular Formula	C₂₀H₂₃F₁₈N₃O₄
Molecular Weight	663.39 g/mol
Synonyms	Florbetapir (18F); AV-45; 2-(3-fluoro-4-(methylamino)phenyl)-7-(2-fluoroethoxy)-5H-pyrido[4,3-b]indole; Amyvid (Brand Name); [18F]AV-45; Florbetapir (18F) Injection; BAY94-9172; Florbetapir F18
EINECS	Contact for details

Quality Control

Our Florbetapir F 18 is manufactured under strict quality systems suitable for radiopharmaceutical applications. Each batch is subjected to rigorous analytical testing, including HPLC for radiochemical purity and identity, to ensure it meets exacting standards. A comprehensive Certificate of Analysis (COA) detailing radionuclidic purity, radiochemical purity, specific activity, pH, and sterility (where applicable) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. This product is strictly light-sensitive and must be protected from all light exposure during storage and handling. Store at controlled room temperature or as specified on the label. Follow all radiation safety protocols.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Identification (HPLC)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 95%
Radionuclidic Purity	≥ 99.9% (F-18)
Specific Activity	Contact for details
pH	4.5 - 7.5
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.